In the middle of the 19th century the ale house of the chemist Prell in inner-city Berlin was so popular that he decided to buy cheap land outside the city to build the urgently required beer cellar for his Berlin brewery. His successors expanded the cellar and they completed it with a Biergarten. Later the brewery was renamed Schultheiss Brewery and was relocated at the city gates: What is today's Prenzlauer Berg became the main headquarters.
In the second half of the 19th century many breweries settled here in Prenzlauer Berg, once known as Mühlenberg. The many Biergarten and halls near the breweries became a popular destination for trips from outside Berlin. Sometimes the Biergarten offered enough space for thousands of guests and on weekends they drew visitors to the city en masse.
With the construction of the breweries and other entertainment places grew also the housing development, and more and more people and Berliners from the inner city moved to this area.
The brewery expanded, starting in the 1890s with the building of the area that is still visible today: a cohesive castle-like group of buildings made of yellow bricks on the outside and red bricks on the inside. After World War One it became the biggest beer brewery in the world. Today the area once known simply for brewing has become a Kulturbrauerei ("culture brewery") and a diverse event venue. Although severely reduced, there is also a Biergarten.